General Cell Based Assays
Cayman Chemical BIlIrubIn ConjugatesodIM500mg
A stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives; exhibits anti-oxidant and antimutagenic effects
Meso Scale Discovery U-PLEX Mouse TNF- ASY
The Meso Scale Discovery U-PLEX Mouse TNF-alpha Assay is a multiplex immunoassay kit that enables simultaneous measurement of mouse tumor necrosis factor alpha (TNF-alpha) in serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and can be fully automated on the MSD instrument platforms The lower limit of detection is 0 04 pg/mL
Meso Scale Discovery U-PLEX Mouse IL-16 ASY
The Meso Scale Discovery U-PLEX Mouse IL-16 Assay is a multiplex immunoassay kit that enables simultaneous quantification of mouse interleukin 16 (IL-16) in serum plasma and cell culture supernatants This electrochemiluminescent assay utilizes MSD s proprietary SECTOR Imager and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies calibrators and controls for generating a standard curve and measuring IL-16 levels accurately This assay allows efficient reproducible analysis of IL-16 an immunomodulatory cytokine involved in inflammatory and autoimmune responses
Eurofins Discoverx PathHunter eXpress mADORA2B CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0469E2MCP0M)
The PathHunter mADORA2B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. NECA) based activation of mADORA2B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mADORA2B and EA-tagged β-Arrestin-2. Activation of mADORA2B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR32 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0321E2ACP2M)
The PathHunter GPR32 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR32 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR32 and EA-tagged β-Arrestin-2. Activation of GPR32 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR61 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0407E2ACP1L)
The PathHunter GPR61 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR61 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR61 and EA-tagged β-Arrestin-2. Activation of GPR61 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress TBXA2R U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0322E3CP5L)
The PathHunter TBXA2R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. thromboxane A2, prostaglandins) based activation of TBXA2R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TBXA2R and EA-tagged β-Arrestin-2. Activation of TBXA2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpressNR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0323E2CP0M)
The PathHunter MLNR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. motilin) based activation of MLNR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MLNR and EA-tagged β-Arrestin-2. Activation of MLNR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress A549 G9a Methyltransferase Assay, 10-plate Kit. (96-0003E15CP7L)
The InCELL Hunter eXpress A549 G9a Methyltransferase Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of G9a via detection of G9a levels. This product uses EFC technology. The cell line included overexpresses G9a target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human Periostin/OSF-2 Assay, Singleplex, SECTOR plates, 5 plates, compatible with MESO SECTOR instruments, Research Use Only
The MESO SCALE DISCOVERY R-PLEX Human Periostin/OSF-2 Assay is a specialized immunoassay designed for the detection of human Periostin/OSF-2. Utilizing advanced electrochemiluminescence technology, this assay ensures high sensitivity and reliability for biomarker discovery and development. The complete kit includes all essential components for easy assay setup and execution, making it ideal for research applications.
- Designed for research use only
- Electrochemiluminescence assay principle
- Singleplex format for specific analyte detection
- Compatible with MESO SECTOR instruments
- Comes with biotinylated capture and SULFO-TAG™ detection antibodies
- Includes calibrator, diluents, and MSD GOLD™ Read Buffer B
- Lower limit of detection calculated at 2.5 standard deviations above background
- Supports multiplexing with other analytes using R-PLEX Assay Designer
- Quick and easy assay development process
Eurofins Discoverx PathHunter eXpress ErbB2-ErbB3 Functional Assay, 10pl Kit. (93-0535E3CP16L)
The PathHunter eXpress ErbB2-ErbB3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated ErbB2 and ErbB3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged ErbB2 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, ErbB3 Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR75 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0363E2ACP1M)
The PathHunter GPR75 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR75 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR75 and EA-tagged β-Arrestin-2. Activation of GPR75 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.